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HMGB-1 |
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The Company's current research and development portfolio includes HMGB-1, a pro-inflammatory substance identified as a mediator of TNF-associated tissue damage; development of small molecule and vagal nerve stimulation approaches to treat inflammation; and CTI-01, a proprietary anti-inflammatory drug candidate currently in Phase I clinical trials. These products include its lead drug (an improved, controlled-release formulation of a drug currently approved for the treatment and prophylaxis of asthma), a cytoprotective drug to reduce trauma-related vascular and organ damage currently in Phase I clinical trials, and biologic products targeting HMGB-1, a novel pro-inflammatory cytokine to treat severe inflammatory diseases in partnership with MedImmune. The Company's current research and development portfolio includes the following therapeutic targets: HMGB-1, a pro-inflammatory substance identified as a mediator of TNF-associated tissue damage; development of small molecule and vagal nerve stimulation approaches to treat inflammation; and CTI-01, a proprietary anti-inflammatory drug candidate currently in Phase I clinical trials. |
HMGB-1 |
HMG CoA HMG CoA HMG CoA reductase HMG CoA reductase HMG CoA reductase inhibitor HMG-1 HMG-14 HMG-17 HMG-CoA HMG-CoA lyase HMG-CoA reductase HMG-CoA reductase HMG-CoA reductase i HMG-CoA reductase i HMG-CoA reductase i HMG-CoA reductase i HMG-CoA reductase inhibitor HMG-CoA reductase inhibitor HMG-CoA reductase inhibitors HMG-CoA reductase inhibitors HMG-CoA synthase deficiency hMG-hCG HMG-I HMG-T HMG1 HMG1/2 HMG12 HMG2 HMGA HMGB HMGB-1 HMGB1HMGC HMGCC HMGCL HMGCoA reductase HMGCoA reductase HMGCR HMGCS HMGCS2 HMGD HMGEL HMGF HMGI HMGI/Y HMGIC HMGN HMGP HMGPA HMGR HMGS HMGT HMH HMHA Hmhb HMHC | |||||
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