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HNPCC

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AcronymDefinition
HNPCCHereditary non-polyposis colon cancer
HNPCCHereditary Non-polyposis Colon Cancer Syndrome (genetics)
HNPCCHereditary Non-Polypotic Colorectal Cancer
HNPCCHereditary Nonpolyposis Colorectal Cancer/Carcinoma


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Five per cent of those diagnosed with bowel cancer have the HNPCC fault - of whom nearly half would have a further defect called MSH2.
Plus the colon cancer gene, HNPCC, is linked to a higher breast cancer risk.
The defect in HNPCC is the mismatch repair gene associated with micro-satellite instability, and has a high lifetime risk of developing CRC (98% in men, 40% in women).
 
 
 
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