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HSP90

   Also found in: Wikipedia 0.01 sec.
AcronymDefinition
HSP9090 kda Heat Shock Protein
HSP90Heat Shock Protein 90


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The team found that Hsp90 and BCL-6 joined together within cancer cells to form a complex.
When the steroid binds to the receptor, the hsp90 dissociates, and the steroid-receptor complex then translocates to the cell nucleus.
Hsp90 is a central component of the cellular chaperone system--a system that supports and stabilizes numerous cancer-causing proteins such as c-Kit, EGFR, and HER2.
 
 
 
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