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HTLV-2Human T Cell Leukemia Virus type 2
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Accordingly, if GD21 and rgp46-1 were positive, the samples were reported as positive HTLV-1 and if GD21 and rgp46-2 were positive, the samples were reported as positive HTLV-2.
15] Unfortunately, further testing to confirm the diagnosis or differentiate between HTLV-1 and HTLV-2 infection was not performed.
HTLV-2 seems to have less pathogenicity, although there are reports of association with neurological diseases similar to HAM/TSP (4).
Gallo, who pioneered the field of human retroviruses with his discoveries of HTLV-1 and HTLV-2, co-discovered HIV as the cause of AIDS, and developed the HIV blood test that has saved many thousands of lives, the IHV meeting brought together the world's leading virologists and HIV researchers to discuss breaking scientific advances to allow better treatment and prevention of both HIV and viruses that cause cancer.
Influence of HTLV-2 infection on hepatitis C virus replication in HIV-positive patients.
While HTLV-2 can also cause neurological disease, it appears to be less common than HTLV-1 infection in Lima (18, 19).
Reactive samples are confirmed by a Western blot (Wb) test, capable of discriminating between HTLV-1 and HTLV-2 infections (Genelabs, Singapore).
From 1995 through 1998, donors were screened for antibodies against HTLV-1 and HTLV-2 by standard ELISA (Abbott HTLV-1/HTLV-2 enzyme immunoassay; Abbott Laboratories, Abbott Park, IL, USA).
The test was found to be highly sensitive by accurately detecting all positives and no cross reactivity was observed with specimens from individuals with non-HIV infections such as Hepatitis B, Hepatitis C, syphilis, HTLV-1, HTLV-2 and CMV.
PTLV-1, PTLV-2, and PTLV-3 include human (HTLV-1, HTLV-2, and HTLV-3) and simian (STLV-1, STLV-2, and STLV-3) viruses (1-6).
Human T-lymphotropic virus type 2 (HTLV-2) provirus in circulating cells of the monocyte/macrophage lineage in patients dually infected with human immunodeficiency virus type 1 and HTLV-2 and having predominantly sensory polyneuropathy.