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CRx-102 has already demonstrated clinical efficacy in three Phase 2a clinical studies, including hand osteoarthritis and rheumatoid arthritis," commented Daniel Grau, Chief Operating Officer of CombinatoRx. CRx-102, an oral synergistic combination containing the cardiovascular drug dipyridamole and an unconventionally low dose of the glucocorticoid steroid prednisolone, demonstrated powerful anti-inflammatory effects and rapid onset of action in both hand osteoarthritis and rheumatoid arthritis: CRx-102 has now demonstrated positive results in three clinical settings, including hand osteoarthritis, in which CRx-102 demonstrated a statistically significant reduction in pain and stiffness as well as improvements in tender and swollen joints. |
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