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0 mg/kg dose, the highest dose tested, achieved an average maximum decrease of viral concentrations in the blood of 98. EBS-A42 was immunogenic at all doses tested, the immune response rate was 83% at the lowest dose tested and 100% at the highest dose tested. Preliminary safety and tolerability data from a recently completed single ascending dose Phase 1 trial in healthy adult male and female volunteers indicated that single doses of PRX-07034 were well-tolerated up to 2500 mg, the highest dose tested. |
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