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HGRHHuman GH (Growth Hormone)-Releasing Hormone
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4) There is no report of Creutzfeldt-Jakob disease after using recombinant human GH either.
00 h) during four weeks, 7 days/week, and (2) young experimental animals, receiving the same injection volume added with recombinant human GH (rHGH, Omnitrope, Sandoz, Spain) (1 mg/k b.
Growth hormone concentration at all time points was determined in duplicate using a human GH enzyme-linked immunosorbant assay (MP Biomedicals, Solon, OH).
The final matrices used for the preparation of calibrators reflect the choices available for materials that are free (or almost free) of human GH but have a matrix comparable to that of human serum.
Findings show RE to significantly elevate human GH concentrations 15~30 minutes after RE (Kraemer et al.
Recombinant human GH replacement increases CD34+ cells and improves endothelial function in adults with GH deficiency.
A recent Cochrane review concluded that there is some evidence that recombinant human GH improves short-term growth and (near) final adult height in children with idiopathic short stature.
Human GH and insulin-like growth factor-1 stimulating and growth promoting effects by long term intranasal administration of the hexapeptide-hexarelin (Abstract).
Older pituitary-derived human GH (hGH) preparations contain a wide variety of isoforms, whereas the newer, recombinant WHO International Standards [Recombinant DNA-Derived Human Growth Hormone, NIBSC (National Institute for Biological Standards) codes 88/624 and 98/574] consist purely of 22-kD GH (8).
Treatment of nonelderly GH-deficient adults with recombinant human GH (rhGH) improves body composition, muscle strength, physical function, and bone density, and reduces blood cholesterol and cardiovascular disease risk, but is often accompanied by carpal tunnel syndrome, peripheral edema, joint pain and swelling, gynecomastia, glucose intolerance, and possibly increased cancer risk.
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