| Acronym | Definition |
|---|
| HFC | Hybrid Fiber-COAX |
| HFC | Hybrid Fiber Coaxial (Cisco) |
| HFC | Household Finance Corporation |
| HFC | Harpers Ferry Center (US National Park Service) |
| HFC | Healthcare Facilities Consortium |
| HFC | Home for Christmas |
| HFC | Harvard Faculty Club (Cambridge, MA, USA) |
| HFC | Hydro-Fluoro-Carbon |
| HFC | Home Front Command (Israel) |
| HFC | Holy Family College (Philadelphia, PA) |
| HFC | Hawthorn Football Club (Australia) |
| HFC | Hormel Foods Corporation |
| HFC | Health and Fitness Club |
| HFC | Hands-Free Calling (OnStar) |
| HFC | High Frequency Current |
| HFC | Hybrid Fiber Copper |
| HFC | High Frequency Correction |
| HFC | Hassle Free Clinic |
| HFC | High Flow Catalytic Converter (automotive) |
| HFC | Harvest Family Church (various locations) |
| HFC | Home Furnishings Council |
| HFC | High Frequency Choke |
| HFC | High Frequency Communication |
| HFC | HalcyonFinance Company |
| HFC | Heritage Forest Campaign (conservation alliance; Washington, DC) |
| HFC | Held for Court (court) |
| HFC | High Force Compaction (nuclear industry) |
| HFC | Histon Football Club (UK) |
| HFC | Howlong Football Club (New South Wales, Australia) |
| HFC | High-Energy Laser Fire Control |
| HFC | Heroes From China (gaming clan) |
| HFC | Horde Flag Carrier (gaming, World of Warcraft) |
| HFC | Heart Failure Center (various locations) |
| HFC | Head Football Coach (various locations) |
| HFC | House Finance Committee (various locations) |
| HfC | Hall for Cornwall (theatre; UK) |
| HFC | Hooker Furniture Corporation (Martinsville, VA) |
| HFC | Hydrogen Fuel Cell |
| HFC | HOPE (Handicapped, Orphaned, Poor and Exploited) for Children (UK) |
| HFC | Heroes for Children (Richardson, TX) |