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Taken together, our morphologic, endocrinologic, and in vino gene activation assay data suggest two hypotheses: a) there is an androgenic substance(s) in the FLE and/or b) there is a mixture of endocrine-active substances that alter the hypothalamic-pituitary-gonadal axis. She gives a lucid review of the latest issues in developmental and behavioral neuroendocrinology, including discoveries about the sexual differentiation of the hypothalamic-pituitary-gonadal axis and an update on the interactions between stress and reproductive function. These neurons are part of the hypothalamic-pituitary-gonadal axis essential in maintaining the delicate balance of GnRH release. |
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