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IC50

   Also found in: Encyclopedia, Wikipedia 0.01 sec.
AcronymDefinition
IC50Median Inhibition Concentration (concentration that reduces the effect by 50%)
IC50Inhibit Cellular Proliferation by 50%


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Further analysis revealed that one of these compounds, 2-(1-hydroxyundecyl)-1-(4-nitrophenylamino)-6-phenyl-6,7a-dihydro-1H-pyrrolo[3,4-b]pyridine-5,7(2H,4aH)-dione (A12B4C3), was the most effective, with an IC50 of 0.
RESULTS: The IC50 of VK3 for pancreatic cancer cells was calculated for 42.
Furthermore, the use of PocketTips has enabled the consistent determination of IC50s of compounds, which have previously presented challenges and variability in results (Figure 4).
 
 
 
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