Early diagnosis in leprosy --Comparing diagnostic tests in a large prospetive study (The INFIR
Ensuring inter-tester reliability of voluntary muscle testing and monofilament sensory testing in the INFIR cohort study.
Early diagnosis of neuropathy in leprosy--comparing diagnostic tests in a large prospective study (the INFIR cohort study).
Similar results were found in INFIR study (10) in which the thermal and vibratory thresholds were decisive in the early diagnosis of neuropathy.
Ensuring inter-tester reliability of voluntary muscle and monofilament sensory testing in the INFIR Cohort Study.
demonstrated that nerves can demonstrate subclinical damage before NFI is clinically detectable.
BPT, Ball-point test; FIN, Filament Index Number; INFIR
, ILEP Nerve Function Impairment and Reaction; MB, Multi bacillary; MDT, Multi drug treatment; MFT, Monofilament test; NFI, Nerve function impairment; PB, Paucibacillary; TENLEP, Treatment of Early Neuropathy in Leprosy; VMT, Voluntary muscle test;
11) van Brakel WH, Nicholls PG, Das L, The INFIR
Dr Peter Nicholls presented a secondary analysis of ENL in the INFIR
Cohort which enrolled 303 MB patients.
We also wish to acknowledge Dr Wim van Brakel for his role in developing the scales used in the INFIR
In the INFIR Cohort which recruited 303 individuals with multibacillary leprosy more than 60% had a reaction or nerve damage at presentation or during the study.
The INFIR Cohort study and the IDEAL consortium are examples of collaborative research programmes that the leprosy community should try to build on.