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Twenty sessions (twice a week) of IRSB of 10 mg guanethidine and 1 mg lidocaine/kg body weight each.
An early randomized trial (3) comparing the efficacy of IRSB with guanethidine versus SGB on 19 patients with CRPS type I demonstrated that 4 patients who received IRSBs with guanethidine (one every 4 days) were comparable with 8 patients on SGBs (1/day) regarding perception of pain, vasomotor disturbances, trophic changes, edema, and range of motion.
However, if the outcome is not satisfactory, IRSBs with guanethidine and lidocaine, according to our protocol, (1) should be employed.