ISKDCInternational Study of Kidney Disease in Children
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Over the years, since the findings of the ISKDC study were published, there have been changes in the population that present with nephrotic syndrome.
The ISKDC study (1981) set dosing guidelines, and these then became the control group for randomized control studies that followed.
The question of when to perform a renal biopsy has been an ongoing discussion since the ISKDC (1978, 1981) published its recommendations.
Two-year outcome of the ISKDC regimen and frequent-relapsing risk in children with idiopathic Nephrotic syndrome.