Normative T-scores are not available for each of the 17 subscales that constitute the ITSEA domain scores; only the raw score percentile ranks are available for each subscale.
Study staff were not aware of a child's ITSEA scores or PBDE exposures through breast milk at the time the HOME was administered.
We used separate multivariate regression models to examine the association between each of the five most detected PBDEs and their sum and the four ITSEA domains.
In comparison to the social and emotional domains measured by the ITSEA in the normative population (mean normative T = 50), children in our sample generally had lower scores on assessments of externalizing behavior problems, internalizing behavior problems, and dysregulation (indicating fewer behavior problems; age- and sex-adjusted domain T-scores: 47.
Supplemental Material, Table S1: Adjusted* associations (Beta) between levels of PBDE congeners in breast milk and ITSEA domains (exposure categorized as below the median, the 50th to the 75th percentile, and above the 75th percentile of congener levels in breast milk).
Although these children were young and the ITSEA is not intended to be used as a diagnostic tool by itself, young children who are later diagnosed with attention deficit/hyperactivity disorder (ADHD) would also be expected to have had high activity/impulsivity subscale scores on the ITSEA (Carter and Briggs-Gowan 2006).
The children in our study sample population generally were reported by their mothers to be performing well on the ITSEA, suggesting appropriate social and emotional develop ment at an average of 30 months of age.