There are then a limited number of variants in NUO marking the relation between A and C: these come to be expanded at IUO.
Progress from NUO to IUO is generally speaking pushed by communicative needs, as the learner at the initial stage requires constant scaffolding (not merely for vocabulary: cf.
In NUO and IUO, the situation is very similar to that described by Silberstein (2001) for L2 German, and Bernini for L2 Italian.
Coenen and van Hout (1988) analyze the Dutch modal moet `must' at IUO as an adverb, which has complementary distribution in column B to the negator niet, and to the emphatic assertion marker wel (lapp.
Nevertheless, the laboratory community is right to be concerned about the guidance document statement that manufacturers should not sell RUO or IUO reagents "to laboratories that they know use the product for clinical diagnostics use.
Several potential problems are associated with the use of RUO and IUO reagents in clinical laboratory testing: (a) the creation of an uneven playing field for manufacturers; (b) the perception that manufacturers or laboratories are defying FDA regulatory authority; and (c) the reporting of inaccurate, misleading, or inconsistent results, either within a laboratory or among several laboratories.
That situation could arise, for example, if an RUO or IUO reagent is not what the vendor says it is or performs in a manner that both is inconsistent with what the vendor states and is unexpected by the clinical laboratory.
In our laboratory, the hs-cTnI IUO assay LoB was determined to be <0.
Analytically, this newer version of the hs-cTnI assay (hs-cTnI IUO) appears to have retained attributes similar to those of the prototype assay, although the estimates for both the LoB and LoD are slightly different (example, hs-cTnI IUO assay LoD = 3 ng/L compared to prototype LoD = 2 ng/L).
4] Nonstandard abbreviations: MI, myocardial infarction; ACS, acute coronary syndrome; CVD, cardiovascular disease; hs-cTnT, high-sensitivity cardiac troponin T; IUO, investigational-use-only; cTnI, cardiac troponin I; HOPE, Heart Outcomes Prevention Evaluation; PVD, peripheral vascular disease; CRP, C-reactive protein; NT-proBNP, N-terminal pro-B-type natriuretic peptide; LoB, limit of the blank; LoD, limit of detection; AUC, area under the curve; HR, hazard ratio; PEACE, Prevention of Events with Angiotensin-Converting Enzyme Inhibition.
Male condom 16% Other 7% IUO
6% Injectable 4% Ring 2% Implant or patch 1% Sterilization 36% Pill 27% Notes Sterilization includes female and male procedures.
Unfortunately, they didn't, or they used the funds for other projects and wrote the pensions an IUO