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IVPI |
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IVPI and ICPI were determined as previously described (3). Groups of 10 chickens were inoculated with the 7 influenza (H5N1) viruses to determine the IVPI index (17). As the occurrence of multiple basic amino acids in the cleavage site marks highly pathogenic H5 and H7 influenza A strains (9), this finding confirms the results of the IVPI experiment. |
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