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Some examples of increased resistive loads during breathing are a decrease in the airway diameter during bronchospasm, increasing flow during high levels of ventilation, and stiffening of the lung tissue in conditions such as interstitial pulmonary fibrosis. Later, however, Finley et al suggested that the alveolar-capillary membrane in interstitial pulmonary fibrosis (IPF) was affected in a non-uniform manner, leading to ventilation/perfusion ([V. |
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