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However, viruses within the H5 and H7 subtypes have the capacity to acquire genetic properties that confer high virulence and a high proportion of deaths in chickens and other fowl after their introduction into domestic poultry; these viruses are characterized as highly pathogenic avian influenza (HPAI) viruses according to the intravenous pathogenicity index method described by the World Organization for Animal Health (1). assay, chicken intravenous pathogenicity index, and reference sera. The intravenous pathogenicity index score of A/chicken/Korea/ IS/2006 was 3. |
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