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JNK
(redirected from Jun N-terminal Kinase)

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AcronymDefinition
JNKJun N-terminal Kinase
JNKJunk (File Name Extension)
JNKJun Nuclear Kinase


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Therefore, we studied the involvement of iron and ROS in the modulation of Jun N-terminal kinase 2 (JNK2) activity, c-jun and c-fos mRNA levels, key signaling steps in the transcriptional control of matrix-degrading metalloprotease (MMP)-1/interstitial collagenase and MMP-3/stromelysin-1 after UVB irradiation of human dermal fibroblasts in vitro.
The selective protein kinase C inhibitor, Ro-31-8220, inhibits mitogen-activated protein kinase phosphatase-1 (MKP-1) expression, induces c-Jun expression, and activates Jun N-terminal kinase.
This suggests that other MAP kinases such as Jun N-terminal kinase and/or p38 kinase might be involved in the activation of SRE at progressively higher concentrations of EGF (26).
 
 
 
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