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KCNQ

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AcronymDefinition
KCNQPotassium Channel, Voltage-Gated, KQT-like subfamily


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ICA- 105665 is a novel, orally available opener of subtypes of KCNQ channels, which have been validated by both genetic and physiologic evidence as playing an important role in certain conditions characterized by abnormal neuroexcitability, such as seizures, and potentially also chronic pain disorders.
ICA-105665 is an activator of certain subtypes of KCNQ ion channels for the potential treatment of a variety of neuroexcitability disorders such as epilepsy and pain.
has reported that the FDA has lifted the partial clinical hold related to the development of ICA-105665, the company's novel orally available small molecule KCNQ potassium channel agonist, for the treatment of epilepsy.
 
 
 
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