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Briefly, the first method, which uses KSHV-infected human KS-1 cells as source of antigens, allows mainly the detection of antibodies directed against lytic KSHV antigens, while the second, using KSHV-infected BC3 cells, allows only for the detection of antibodies directed against the latent nuclear antigen. 3,5,6,9) In the presence of HIV, KS is associated with human herpesvirus 8 (HHV-8, also referred to KSHV for KS-associated herpesvirus). The physicians detected KSHV in certain bone marrow cells of 15 multiple myeloma patients. |
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