| Acronym | Definition |
|---|
| KC | Kansas City |
| KC | Kilocycle (now kilohertz) |
| KC | Airborne Fuel Tanker/Cargo (military aircraft designation) |
| KC | Casey (Harry Wayne Casey of KC and the Sunshine Band) |
| KC | Kansas City Chiefs (NFL football) |
| KC | King County |
| KC | Kennel Club |
| KC | Kenny Chesney (country music artist) |
| KC | Kaiser Chiefs (band) |
| KC | Kelly Clarkson (singer) |
| KC | King Crimson (band) |
| KC | Kurt Cobain (late lead singer of Nirvana) |
| KC | Kids Club |
| KC | Kern County (California) |
| KC | Knights of Columbus |
| KC | King's College (UK) |
| KC | Kingston Communications (UK) |
| KC | Kings Canyon (California) |
| KC | Key Club |
| KC | Kings County (California) |
| KC | King Crab |
| KC | Keratoconus (medical; eye condition) |
| KC | Kyocera Corporation |
| KC | Key Customer |
| KC | Kupffer Cell |
| KC | Fracture Toughness |
| KC | Keratinocyte-Derived Chemokine |
| KC | Knight Commander (Orders of Chivalry) |
| KC | Kent City (Michigan) |
| KC | Key Concern |
| KC | Kalamazoo College (Kalamazoo, Michigan) |
| KC | King's Counsel |
| KC | Knight Commander (game) |
| KC | Keiser College (Decatur, Georgia) |
| KC | Key Characteristic (process engineering) |
| KC | Kings of Chaos (gaming group) |
| KC | Koprivnica, Croatia (license plate) |
| KC | Kevlar Carbon (composite fabric) |
| KC | Kennel Club of Great Britain (original kennel club) |
| KC | Konala Cartelli (Finnish hiphop group) |
| KC | Kreb's Cycle (biology) |
| KC | Knowledge Category |
| KC | Katong Convent (Singapore) |
| KC | Karnors Castle |
| KC | Keppel Club (Singapore) |
| KC | Strikeout Called (scorer's abbreviation) |
| KC | Keyboard Cowboys |
| KC | Khmerconnection (Cambodian web portal) |
| KC | Kept Child (adoption) |
| KC | Kanawha Central (railroad) |
| KC | Kaineng Center (gaming, GuildWars) |
| KC | Kilo Character (computer hierarchy memory measure) |
| KC | Kicking Center (long snapper on placekicks; pro football) |