It has been theorized that the effects of verapamil in CPVT are due to a reduction in the primary calcium signal through blockade of the L-type calcium channel
Figures 4(c) and 4(d) show that the current amplitude of L-type calcium channel
at +10 mV was not affected by STV either.
The plasma membrane contains calcium ATPase (PMCA) pump, L-type calcium channels
, Cl-ca channel, a leak and inward rectifier potassium channels.
In most neurons, multiple mechanisms exist whereby increases in intracellular calcium concentration may occur including for example in calcium entry through N-methyl-D-Aspartate (NMDA) glutamate receptors and various voltage-gated calcium channels such as L-type calcium channels
(LTCC), as well as in the release of calcium from intracellular stores [13-15].
Calcium channel blockers inhibit calcium ion flow through L-type calcium channels
sensitive to voltage .
Blockade of spinal n-type and p-type but not l-type calcium channels
excitability of rat dorsal horn neurones produced by subcutaneous inflammation ity of rat dorsal horn neurones produced by subcutaneous inflammation.
7] M), a L-type calcium channels
blocker and atropine (3 x [10.
L-Type calcium channels
mediate a slow excitatory synaptic transmission in rat midbrain dopaminergic neurons.
2 and SUR2A and the inhibition of calcium influx via the L-type calcium channel
by decreasing the expressions of Cav1.
Characterisation of marrubenol, a diterpene extracted from Marrubium vulgare, as an L-type calcium channel
Inhibitory effect of magnolol on L-type calcium channel
currents and expression of [[alpha].
In the additional experiment, following the addition of different concentrations of DG, the L-type calcium channel
opener BAY-K8644 (0.