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L1CAM

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AcronymDefinition
L1CAML1 Cell Adhesion Molecule


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The L1CAM is typically expressed on neural cells and plays an important role in neurogenesis, nerve growth, and neuron-to-neuron adhesion.
Table 3: X-linked HSP Gene locus Chromosome Protein Special location name features SPG 1 Xq L1CAM "CRASH" phenotype (see text) SPG 2 Xq Proteolipid "pure"HSP protein to PMD (see gene text) Gene locus Severity Typical Number of onset age families known SPG 1 Moderate Congenital >100 (not all to severe or infancy have spastic paraplegia as main symptom) SPG 2 Mild to Infancy to >100 (most severe teens have PMD phenotype) Dr.
 
 
 
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