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LDLR |
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? References in periodicals archive |
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The LDLR (low density lipoprotein receptor) gene test offered by Correlagen can diagnose FH and can identify a mutation in family members who may not have abnormal cholesterol levels. Contrary to the accepted hypothesis positing downregulation of low-density lipoprotein receptor (LDLR) in humans, expression of the human APOE4 isoform combined with increased LDLR was harmful in genetically modified mice when red a high-fat Western diet, predicting important interactions between genotype/phenotype and exposure. |
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