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LOEL |
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25 mg/kg/day rats UF = 100 LOEL = 75 mg/kg based on observations of clinical signs such as aggression, abnormal/decreased movement, and increased body temperature (c) Resmethrin NOEL = 10 mg/kg/day (d) Based on liver weight RfD = 0. This LOEL was based on a modified Tasker scoring system (Tasker et al. Thus, group size must be sufficiently large to detect low-dose effects and to distinguish a LOEL from a true NOEL. |
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