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LPAI |
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Theories suggest that HPAI viruses emerge from H5 and H7 LPAI progenitors by mutation or recombination (2,3), although >1 mechanism is likely. Direct sequencing is relatively time-consuming and laborious and thus is not suitable for local and regional diagnostic laboratories that receive large numbers of samples that may contain HPAI or LPAI subtype H5N1. Wild birds harbor the LPAI ancestral viruses of HPAI strains of poultry (and mammals). |
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