Because of its location and various histologic patterns as has been described, LSMFT can mimic a variety of lesions.
12) It is in this higher stage that intraosseous lipoma and LSMFT can become confused; LSMFT can also show lipomatous areas with involutional and ischemic change.
This lesion can present with a similar radiographic image to that of LSMFT, but its occurrence in the lower femur and in young adults distinguishes it from LSMFT.
In summary, the histologic features of LSMFT may suggest a variety of entities for consideration in the differential diagnosis.
2,3) Some authors report a risk as high as 10%, with malignancies such as osteosarcoma and malignant fibrous histiocytoma identified in a background of LSMFT.