2-41) The majority of our subjects were Christians (90% of the group who declined LTOP and 80% of those who accepted; p>0.
9) reported an 86% uptake for LTOP for severe fetal anomaly.
All 5 of the women in our study who decided on LTOP had no regrets about their decision, while 2 of the 10 who opted to continue their pregnancies regretted the decision after seeing the baby.
In contrast to findings reported by others, (10-12) all the women in our study who opted for LTOP felt that they had made the right decision, even though it was a painful one, after confirmation that the fetus was severely malformed or would suffer severe morbidity should it survive.
The relatively low uptake of LTOP for severe fetal anomaly in this study compared with a previous report from this unit is probably due to the small sample size.
LTOP for severe congenital abnormalities was offered to 253 women (study group), of whom 191 (75.
The most frequent indications for LTOP were brain and spinal abnormalities (53.
There were 27 cases of spina bifida, and in this group 16 women accepted LTOP.
The mean interval between diagnosis and feticide was 10 days (range 0-42); 53 women accepted but did not have LTOP feticide.
In South Africa, there are no known national data on LTOP and feticide for fetal abnormalities, nor are there guidelines and legislature on feticides.
In KZN, the Fetal Medicine Unit at IALCH has established guidelines for LTOP.
The highest acceptance rate for LTOP was in women between the ages of 25 and 34 (80.