| Acronym | Definition |
|---|
| LACE | LWR (Light Water Reactor) Aerosol Containment Experiment |
| LACE | Listening and Communication Enhancement |
| LACE | Liquid Air Cycle Engine |
| LACE | Low-Power Atmospheric Compensation Experiment |
| LACE | Lunar Atmospheric Composition Experiment |
| LACE | Length-Based ASCII Compatible Encoding |
| LACE | Listening and Auditory Communication Enhancement |
| LACE | Laser-Assisted Chemical Etching |
| LACE | Laws and Customs of the Eldar (JRR Tolkien essay) |
| LACE | Local Automatic-Circuit Exchange |
| LACE | LAC Electronics |
| LACE | Laser Atmospheric Compensation Experiment |
| LACE | Life After Cancer Epidemiology study |
| LACE | Laboratorio di Antenne e Compatibilità Elettromagnetica (Italian: Laboratory of Antennas and Electromagnetic Compatibility) |
| LACE | Laser Atmospheric Communications Equipment |
| LACE | Lindenberger Aerosol Characterization Experiment |
| LACE | Locally Adaptive Contrast Enhancement (medical imaging) |
| LACE | Laboratory for Assisted Cognition Environments |
| LACE | Location Ammunition Casualties and Equipment |
| LACE | Laser Communication Experiment |
| LACE | Licensed Agent's Clerical Employee |
| LACE | Low-Altitude Control Enhancements |
| LACE | Liquid (water), Ammunition on hand, Casualties (friendly only), essential Equipment (military radio call for status of) |
| LACE | Lectin Affinity Capillary Electrophoresis |
| LACE | Language and Cultural Exchange (various locations) |