| Acronym | Definition |
|---|
| LIFE | Lifetime Television (cable network channel) |
| LIFE | Life and Health Insurance Foundation for Education |
| LIFE | Losartan Intervention for Endpoint Reduction in Hypertension (drug trial) |
| LIFE | Living in Faith Everyday |
| LIFE | Learning in Informal and Formal Environments |
| LIFE | Laboratory for International Fuzzy Engineering |
| LIFE | Literacy Is for Everyone |
| LIFE | Lingnan Institute of Further Education (Hong Kong) |
| LIFE | Legal Immigration Family Equity Act of 2000 |
| LIFE | Living in Fear Everyday |
| LIFE | Lasallian Institute for the Environment |
| LIFE | Leaders in Fitness Education (Australia) |
| LIFE | Laser-Induced Fluorescence Emission |
| LIFE | Living Implants From Engineering |
| LIFE | Laser IRCM (Infrared Countermeasures) Flyout Experiment |
| LIFE | Community Financial Instrument for the Environment |
| LIFE | Light-Ion Facility Europe |
| LIFE | Living In Fullness Everyday |
| LIFE | Laser Infrared Flyout Experiment |
| LIFE | Live in Freedom Everyday |
| LIFE | Likelihood Function Estimation |
| LIFE | Live in Full Effect |
| LIFE | Leaders in Freshman Engineering (Texas A&M) |
| LIFE | Long Island Fiber Exchange Inc. |
| LIFE | Long Island Funders Exchange (New York) |
| LIFE | Less Intensive Farming and Environment Project |
| LIFE | Local Independent Framing Expert |
| LIFE | Lawrence Inter-Faith Endeavor (food bank in Lawrence County, Indiana, USA) |
| LIFE | Living Injury Free Everyday |
| LIFE | Livingston's Informed Friends of the Environment |
| LIFE | Lessons Intended for Everyone (R. King & Associates) |
| LIFE | Learning Immune Functioning Enhancement |
| LIFE | Loyalty Integrity Fairness Excellence (Nassau County Police Department's Mission Statement, Long Island, NY, USA) |
| LIFE | Laboratory Initiated Fetal Emplacement |
| LIFE | Look.Inward.For.Evolution (self-development workshops conceived by Alan Mallinick) |
| LIFE | Legacies Involving Future Empowerment |
| LIFE | Lobby for the Individual Freedom and Equality |
| LIFE | Linear Information Flow Edge-Following (network communication algorithm) |