| Acronym | Definition |
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| LOE | Ley Orgánica de Educación (Spanish) | | LOE | Level Of Effort | | LOE | Live Operating Environment | | LOE | Letter of Explanation | | LOE | Limited Objective Experiment | | LOE | Language Other than English. | | LOE | Letter of Engagement | | LOE | Lack of Effort | | LOE | Loss Of Energy | | LOE | Letter Of Evaluation | | LOE | Line Oriented Evaluation | | LOE | Loss of Exclusivity (pharmaceuticals going off-patent) | | LOE | Lesbians On Ecstacy (band) | | LOE | Letter Of Employment | | LOE | Light-Off Examination | | LOE | Limit of Error | | LOE | Line of Effort (US DoD; US NASA) | | LOE | Lease and Operating Expense | | LOE | Landing on Earth | | LOE | Learning and Organizational Effectiveness | | LOE | Line of Engagement | | LOE | Lost on Earth (gaming) | | LOE | Love, As Ever (complimentary closing to letters of endearment) | | LOE | Legacy of Excellence (award) | | LOE | Legions of Evil (computer game) | | LOE | Limit Of Exploitation | | LOE | Length of Engagement | | LOE | Loss Of Effect | | LOE | Letter of Execution | | LOE | Life of Edition (publishing) | | LOE | Legends of Eternity | | LOE | Loss of Excitation (generator protection) | | LOE | Letter of Excellence | | LOE | Level of Edit | | LOE | Loss of Earning Evaluation | | LOE | Left Otitis Externa | | LOE | Local Order Entry | | LoE | Lords of Eriador (gaming guild) | | LOE | Limited Object Expert (related to Business Objects in IT software development) | | LOE | Living Off Equity | | LOE | Loyalty Over Everything (band) | | LOE | Loyal Order of Elbows | | LOE | Liquid Organic Energy (vegetable oil/fat fuel) |
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