| Acronym | Definition |
|---|
| LPI | Linux Professional Institute (Linux) |
| LPI | Lunar and Planetary Institute |
| LPI | Lines Per Inch |
| LPI | Low Probability of Intercept |
| LPI | Lightning Protection Institute (Harvard, Illinois) |
| LPI | Language Proficiency Index |
| LPI | Living Planet Index |
| LPI | Language Proficiency Interview |
| LPI | Laser Peripheral Iridotomy (glaucoma treatment) |
| LPI | Lysinuric Protein Intolerance |
| LPI | Licensed Private Investigator |
| LPI | Libyan Petroleum Institute (Tripoli, Libya) |
| LPI | Low-Pressure Injection |
| LPI | Land & Property Information (NSW, Australia) |
| LPI | Laps Per Incident (racing) |
| LPI | Linkoping, Sweden - Saab (Airport Code) |
| LPI | Late Payment Interest |
| LPI | Low Pressure Inflator (SCUBA) |
| LPI | Last Patient In (clinical trials) |
| LPI | Lead Program Integrator |
| LPI | Licensed Plumbing Inspector |
| LPI | Linder Publishing Inc. |
| LPI | Laser Plasma Instability |
| LPI | Liquid Photo Imaging |
| LPI | Low Probability of Interference |
| LPI | Last Paid Installment |
| LPI | Louisiana Pain Initiative |
| LPI | League of Paranormal Investigators |
| LPI | Loss Prevention Investigator |
| LPI | Louisiana Polytechnic Institute (now Louisiana Tech University) |
| LPI | Launch Package Integration |
| LPI | Labarge Products, Inc (St. Louis, MO) |
| LPI | Little People of Ireland |
| LPI | Liquid Penetration Inspection |
| LPI | Launching Position Indicator |
| LPI | Log-Polar Image |
| LPI | Law Protection Inc. (Canada) |
| LPI | Land Policy Institute (Michigan State University) |
| LPI | Live Production Institute (Las Vegas, NV) |