| Acronym | Definition |
|---|
| LCS | Liberty City Stories (Grand Theft Auto game) |
| LCS | Laboratory for Computer Science (MIT) |
| LCS | Littoral Combat Ship |
| LCS | Live Communications Server |
| LCS | League Championship Series (Baseball) |
| LCS | Low Cost (Laser) Seeker |
| LCS | Liquid Cooling System |
| LCS | Longest-Common-Subsequence (algorithm) |
| LCS | Local Coordinate System |
| LCS | Last Comic Standing (TV series) |
| LCS | Location Services (GSM) |
| LCS | Learning Classifier System |
| LCS | Local Comic Shop |
| LCS | Least-Cost Selection (finance) |
| LCS | Life Cycle Support |
| LCS | Liquid Crystal Shutter |
| LCS | Laboratory Control Sample |
| LCS | Landing Craft, Support |
| LCS | Leachate Collection System (waste management) |
| LCS | Liberal Crime Squad (gaming) |
| LCS | Low Carbon Steel |
| LCS | Literary and Cultural Studies |
| LCS | Low Contact Stress |
| LCS | Lion Country Safari (Florida) |
| LCS | Lagrangian Coherent Structures |
| LCS | Linux Compatibility Standard |
| LCS | Lithuanian Center Union (Lithuania) |
| LCS | Lewis Carroll Society (UK) |
| LCS | Land Combat Systems |
| LCS | London Controlling Section (WWII British organisation responsible for Military Security, Cryptanalysis and Deception Operations) |
| LCS | LAHET Code System |
| LCS | Lane Control Signs (intelligent transportation systems) |
| LCS | Low Cost Sourcing |
| LCS | Las Canas, Costa Rica (Airport code) |
| LCS | Lotus Communication Server |
| LCS | Lie, Cheat, Steal |
| LCS | Littlehampton Community School (UK) |
| LCS | Lifetime Cancer Screening |
| LCS | Library Circulation System |
| LCS | Laser-Compton Scattering (imaging) |
| LCS | Lynx Certifiable Stack (LynxOS) |
| LCS | Lightwave Communication Systems |
| LCS | Large Capacity Storage |
| LCS | Limiting Control Settings |
| LCS | Last Clan Standing (gaming) |
| LCS | Laser Communication System |
| LCS | Ladies Charitable Society (UK) |
| LCS | Local Cache Server |
| LCS | Laser Countermeasure System |
| LCS | LCAC Control Ship |
| LCS | Libyan Cardiac Society |
| LCS | Linfield Christian School (Temucula, California) |
| LCS | Low Curie Salt (waste management) |
| LCS | Laser Crosslink System |
| LCS | Line Conditioning Signals (ITU-T Rec. T.30) |
| LCS | Lost Carbonate Sintering (electronic materials) |
| LCS | Laboratory Computer System (EPA) |
| LCS | Local Call Simulator |
| LCS | Laser Cross Section |
| LCS | Life Cycle Status |
| LCS | laser communication systems |
| LCS | Laverda Club Schweiz (German; motorcycle club; Switzerland) |
| LCS | Launch Control Station |
| LCS | Leakage Collection System |
| LCS | Line Communication Superintendent (Canadian military) |
| LCS | Left Control Strategy |
| LCS | Locomotive Control System |
| LCS | Line-Card-To-Switch Protocol (PMG-Sierra) |
| LCS | Limited Concentrated Sweets (diet) |
| LCS | Lightweight Camouflage System |
| LCS | Label Controlled Switch (Cisco) |
| LCS | Life Cycle Selling |
| LCS | Large Capitalization Stocks |
| LCS | Lake Chelan Shores |
| LCS | Lifescape Community Services |
| LCS | Line Control Shelf (Nokia) |
| LCS | Low order Connection Supervision (Alcatel) |
| LCS | LANTIRN Control Software |
| LCS | Load Carrying Structure |
| LCS | Lagawe Central School (Philippines) |
| LCS | Low-Cost Sonobuoy/Seeker |
| LCS | Local Communications Services (Sprint) |
| LCS | Logistics Cost Sharing |
| LCS | Loan Consolidation System (US Department of Education) |
| LCS | Lexus Customer Service |
| LCS | Lamut Central School |
| LCS | Lighted Candle Society (anti-pornography society) |
| LCS | Lynchburg City Schools (Lynchburg, VA) |
| LCS | Law Career Services (various schools) |
| LCS | Little Chimp Society |
| LCS | Legislative Council Staff (Colorado) |