| Acronym | Definition |
|---|
| LSS | Lean Six Sigma |
| LSS | Large Scale Structure |
| LSS | Lutheran Social Services |
| LSS | Logistics Support System |
| LSS | Legal Services Society (Canada) |
| LSS | Local School System |
| LSS | Line Sharing Service (telecommunications, Australia) |
| LSS | Life Support System |
| LSS | Laboratory for Student Success |
| LSS | Lumbar Spinal Stenosis |
| LSS | Law Students Society |
| LSS | Law Students' Society |
| LSS | Terre-De-Haut, Guadeloupe (Airport Code) |
| LSS | Life-Span Study |
| LSS | Lifesaving Society (Canada) |
| LSS | Last Song Syndrome |
| LSS | Life Saving Service (precursor to US Coast Guard) |
| LSS | Leveraged Super Senior (investing) |
| LSS | Lightweight Shotgun System |
| LSS | Lincoln Square Synagogue (New York, New York) |
| LSS | Life Safety System |
| LSS | Logistics Support Squadron |
| LSS | Large Sample Size |
| LSS | Link Status Signal (SONET) |
| LSS | Local Scrapbooking Store |
| LSS | Life Support Subsystem |
| LSS | Loop Switching System |
| LSS | Limited Stop Service (India busses) |
| LSS | Licensing Support System |
| LSS | Laser Subsystem |
| LSS | Lab Support Services |
| LSS | LATA Switching System (Bellcore) |
| LSS | Lightning Sensor System |
| LSS | Local Switching System |
| LSS | Littoral Surveillance System |
| LSS | Loss of Sequence Synchronization |
| LSS | Link Signaling Sublayer |
| LSS | Lawrence Sheriff School (England) |
| LSS | Laboratory Shift Superintendent |
| LSS | Literature Search System |
| LSS | Labrador State School (Gold Coast, Australia) |
| LSS | Logistics Support Summary |
| LSS | Logical Source Statements |
| LSS | Licensed Software System |
| LSS | Laminated/Stainless Steel |
| LSS | Logistic Support Site |
| LSS | LightStream Switching (Cisco) |
| LSS | Limited Storage Site |
| LSS | Load Scaling Sensitivity |
| LSS | Low Speed Switch |
| LSS | Lunar Soil Stimulant |
| LSS | Large SICPS Shelter |
| LSS | Logistic Support Summary |
| LSS | Line of Sight Sensor |
| LSS | Large Studio System |
| LSS | Launch Sequence Simulator |
| LSS | Launch Status Summarizer |
| LSS | Least Square Straight Line (regression line) |
| LSS | Ligament Suspension System |
| LSS | Lightguide Shelf Splice (AT&T) |
| LSS | Limiting Safety Setting |
| LSS | LEC Settlement System (telephony/communications) |
| LSS | Local Service Server |
| LSS | Limited Service Scheduling |