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LIFE |
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52) However, in the Losartan Intervention For Endpoint reduction in hypertension study, the ARB was associated with a 25% lower incidence of new-onset diabetes than [beta]-blocker therapy, even though the majority of patients in both groups were treated with a diuretic; this suggests a potentially mitigating effect of RAS blockade. Reduction in the Risk of Stroke: The Losartan Intervention For Endpoint reduction in hypertension (LIFE) study was a multinational, double-blind study comparing losartan and atenolol in 9193 hypertensive patients with ECG-documented left ventricular hypertrophy. In the Losartan Intervention for Endpoint Reduction in Hypertension (LIFE) study, presented at the American College of Cardiology meeting in March, COZAAR significantly reduced the combined risk of cardiovascular death, heart attack and stroke as compared to |
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