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LoxP

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AcronymDefinition
LoxPLocus of Crossover in P1 (genetics)


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The cell lines of the present invention can be obtained by integrating both a nucleotide sequence encoding tamoxifen-induced Cre recombinase and a nucleotide sequence encoding insulin regulated by glucose-sensitive promoter into the chromosome in a human immortalized hepatic cell line FERM BP-7498 containing the TERT gene inserted in between a pair of LoxP sequences.
The enzyme, Cre recombinase, or simply Cre, recognizes short viral DNA sequences called loxP sites.
 
 
 
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