M918T

AcronymDefinition
M918TReplacement of Methionine at Position 918 with Threonine (molecular biology)
References in periodicals archive ?
Typing for C634R in exon 11 and M918T in exon 16 confirmed previous genotyping of four wild-type individuals and six heterozygotes for the codon 634 change, and eight wild-type individuals and two heterozygotes for the codon 918 change.
In most clinical laboratories, the direct sequencing of exons containing hotspots of the RET protooncogene is routinely performed in all MTC patients (except for cases in which MEN 2B is suspected, where a direct analysis of the M918T mutation is the first step of the molecular evaluation).