MAPEGMembrane-Associated Proteins in Eicosanoid and Glutathione
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13 500 56 TXS TXS 7q34 533 60 Structural Tissue characteristics distribution PGES mPGES-1 MAPEG family Inflamed tissues, cancerous tissues, kidney mPGES-2 Glutaredoxin/ Almost all tissues thioredoxin-like cPGES -- Almost all tissues PGDS H-PGDS Glutathione-S- Mast cells, transferase microglia, Th2 cells, etc.
All classes of MAPEG were mainly expressed in brain, heart, spleen, kidney, intestine and liver.
Previous reports have described 9 classes of carp GST genes from three GST subfamilies: MAPEGs (mGST1, mGST2 and mGST3), Kappa from the mitochondrial GSTs, and the cytosolic GSTs (Mu, Alpha, Theta, Pi and the Rho which is special in fish and shares no molecular homologue in mammals) (Konishi et al.
Most GST proteins include 200 to 250 amino acids except for MAPEGs (MGST1.