| Acronym | Definition |
|---|
| MASC | Multicast Address-Set Claim (protocol) |
| MASC | Municipal Association of South Carolina |
| MASC | Master of Applied Science |
| MASC | Multidimensional Anxiety Scale for Children |
| MASC | Massachusetts Association of School Committees |
| MASC | Maryland Association of Student Councils |
| MASC | Multinational Arabidopsis Steering Committee (molecular biology) |
| MASC | Massachusetts Association of Student Councils |
| MASC | Multiple-Award Schedule Contract |
| MASC | Michigan Association of Student Councils (Lansing, Michigan) |
| MASC | Medical Academic Staff Committee (British Medical Association; UK) |
| MASC | Myomer Accelerator Signal Circuitry (Mechwarrior Universe games) |
| MASC | Myotube-Associated Specificity Component |
| MASC | Matsushita Avionics Systems Corporation |
| MASC | Michigan Association of Senior Centers |
| MASC | Multiple Access Source Code |
| MASC | Maximum Allowable Stack Concentration |
| MASC | Mission and Safety Critical |
| MASC | Marine Aquarium Society of Colorado (web forum) |
| MASC | Modeling Analysis & Simulation Center |
| MASC | Maintenance and Support Concept |
| MASC | Marine Air Ground Task Force Automated Service Center |
| MASC | Marconi Advanced Scrambler |
| MASC | Multiarray Signal Conditioner |
| MASC | Multiple-Antenna Signal Constellation |
| MASC | Massachusetts Avenue Surgery Center (Bethesda, MD) |
| MASC | Maintenance Support Concept |
| MASC | Michigan Association of Service Coordinators |
| MASC | Mission d'Appui à la Situation de Crise (French: Crisis Situation Support Mission) |
| MASC | Mount Alexander Shire Council (Australia) |
| MASC | Manitoba Agricultural Services Corporation (Canada) |