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MC4R |
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In addition to the FTO and MC4R genes already known, it was now possible for six more obesity genes to be identified: TMEM18, KCTD15, GNPDA2, SH2B1, MTCH2, and NEGR1. What is known is that serotonin activates certain neurons and melanocortin-4 receptors (MC4R) in the brain, that not only curb appetite but also block the effect of other neurons that would normally increase appetite by blocking the effect of MC4Rs. The team believe the gene sequence controls the activity of the MC4R gene, which has previously been linked to rare and extreme cases of childhood obesity. |
MC4R |
MC-VFC MC/A/N/AF/MC MC/BIU MC/CS MC/DC MC/HPF MC/LD MC/PS MC/SC MC/VSF MC:WA MC02 MC1 MC12 MC16 MC2 MC2A MC2A-X MC2C MC2K MC2R MC3 Mc4 MC4J MC4R MC5MC6 MC68000 MC68010 MC68020 MC68030 MC68040 MC6809 MCA MCA MCA bus MCA-5 MCA-I MCA-USA MCA/CCA MCA/CCAO MCA/DD MCA/MCC MCA/MR MCA/VT MCAA MCAAA MCAAC MCAAF MCAAH | |||||
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