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MCASE |
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The Danish EPA also used the MCASE fathead minnow model to predict acute aquatic toxicity of substances. The models used include the MCASE Model A2E (Ashby and Tennant 1991; structural alerts for DNA reactivity), model A62 (induction of micronuclei), model A2H [Salmonella (Ames) mutagenicity], model A61 (chromosomal aberrations), and model A2F (mutations in mouse lymphoma) as well as TOPKAT Salmonella (Ames) mutagenicity model. |
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