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Related to MEN2a: MEN2B
MEN2aMultiple Endocrine Neoplasia, Type 2a (genetic disorder)
References in periodicals archive ?
The Edmans are encouraging everyone else on Fran Edman's side of the family to find out if they also have MEN2A, because "the darn thing is present in every cell in the body," Brennan said.
In MEN2B the 918 mutation alters the substrate specificity of RET tyrosine kinase and induces a different set of signalling pathways to those in MEN2A.
While a number (20%) of MTCs are associated with the autosomal-dominant inherited multiple endocrine neoplasia (MEN) syndromes (specifically MEN2A and MEN2B), most (80%) cases are sporadic.