MERTKTyrosine Kinase Protooncogene
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Patients with loss of MERTK function have a defect in phagocytosis - a mechanism used to remove pathogens and cell debris.
The researchers plan to deliver the MERTK gene in a viral vector a carrier commonly used to deliver genetic material to treat these cells in order to restore function of photoreceptors.
It showed that viral vector delivery of MERTK corrected the mutant gene and restored vision.