In the first MFMU Network study, there were no cases of uterine rupture among a cohort of 15,801 women who underwent elective repeat cesarean delivery, and in the second multicenter study of 25,000 women, this patient group had a rupture rate of 0.
The model in this analysis, which used probability estimates from the MFMU Cesarean Registry, took a longer-term view by including probabilities of outcomes throughout a woman's reproductive life that were contingent upon her initial choice regarding TOLAC (Am J Perinatol.
One of these tools is available at the MFMU Network website (http://mfmu.
In 2005, for instance, the MFMU
reported that a previous vaginal delivery was the most significant predictor of VBAC delivery success in a cohort of 29,661 women with a history of one prior cesarean delivery Women with a prior vaginal birth had a VBAC delivery success rate of 86.
Guzman speculated that the difference in findings between the MFMU
network study and his study may be related to differences in populations in terms of socioeconomic status and care received, and noted that further study is needed as progesterone is now the standard of care in women who have had a previous preterm birth.