Behera et al (22) reported MIC90
values of tigecycline against MRSA and VRE as 0.
For ETEC, MIC90
levels had increased by twofold or greater for all the commonly used antibiotics.
06 og/ml) was eight and 16-fold more active than daptomycin (DAPT) and vancomycin (VANC), respectively against SA; with MSSA and MRSA having the same MIC90
MIC50 and MIC90
of staphylococcal antibiotics against community-acquired methicillin resistant Staphylococcus aureus (CA-MRSA) from Europe (46 isolates), United States (22 isolates), and Oceania (13 isolates) Isolates from Europe Antibiotics MIC50 mg/L MIC90
mg/L Range mg/L Benzyl-penicillin 8 8 0.
Overall antibiotic susceptibilities were consistent with the previously reported MIC90
values for the three antibiotics.
Solithromycin had greater potency than telithromycin, with MIC50 and MIC90
values of one and two micrograms/mL, respectively.
Although all O1 isolates were sensitive to chloramphenicol, there was only a twofold difference in MIC90
to chloramphenicol between O1 and O139 isolates.
At day ten for the 450 mg per day multiple-dose group, the mean OPT-80 stool concentration exceeded 10,000 times the MIC90
(minimum concentration of a drug needed to inhibit growth of 90 percent of microorganisms) of C.
These levels were well above MIC90
, the concentration necessary to inhibit bacterial growth of staphylococcus aureus, staphylococcus epidermidis, and streptococcus pneumonia (</= MIC90
= 250 ng/ml).