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MMAE

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AcronymDefinition
MMAEMechanical, Materials and Aerospace Engineering
MMAEMonomethyl Auristatin E
MMAEMultiple Model Adaptive Estimation (Bayesian technique using Kalman filters)
MMAEMultiple Model Adaptive Estimator


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? References in periodicals archive
In an oral presentation, preclinical data show that SGN-35 effectively targets CD30 and delivers MMAE to tumor cells resulting in potent cell-killing.
Seattle Genetics Announces Advancements in Development Programs at ... by Business Wire
The ADC is designed to be stable in the bloodstream, but to release MMAE upon internalization into CD30-expressing tumor cells, resulting in a targeted cell-killing effect.
Seattle Genetics Initiates Phase I Clinical Trial of SGN-35 by Business Wire
This ADC technology employs synthetic, highly potent drugs, such as MMAE, that can be attached to antibodies through proprietary linker systems.
Seattle Genetics Receives U.S. Patent Relating to Its Antibody-Drug ... by Business Wire
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