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mTOR |
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Amgen is developing a monoclonal antibody (MAb) drug, denosumab, for bone loss in postmenopausal osteoporosis and in oncology indications; Ariad is developing nonbisphosphonate compounds that target both bone and the mammalian target of rapamycin (mTOR), a signaling kinase that is central to disease pathways in many types of cancer. Amgen is developing a monoclonal antibody (MAb) drug, denosumab, for bone loss in postmenopausal osteoporosis and in oncology indications; Ariad is developing nonbisphosphonate compounds that target both bone and the mammalian target of rapamycin (mTOR), a signaling kinase that is central to disease pathways in many types of cancer. |
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