| Acronym | Definition |
|---|
| MSC | Master of Science (degree) |
| MSC | Mathematics Subject Classification |
| MSC | Marine Stewardship Council |
| MSC | Maritime Safety Committee (IMO) |
| MSC | Military Sealift Command |
| MSC | Meteorological Service of Canada |
| MSC | Mobile Switching Center |
| MSC | Mesenchymal Stem Cell |
| MSC | Multimedia Super Corridor (Cyberjaya, Malaysia) |
| MSC | Map Service Center |
| MSC | Modern Steel Construction (AISC magazine) |
| MSC | Memorial Student Center |
| MSC | Manned Spacecraft Center (currently Johnson Space Center) |
| MSC | Management Services Center |
| MSC | Message Sequence Chart |
| MSC | Michael Schumacher (automobile race driver) |
| MSC | Most Significant Change (participatory impact monitoring technique) |
| MSC | Medical Service Corps |
| MSC | Mobile Switching Centre (BT) |
| MSC | Member Service Center |
| MSC | Missionaries of the Sacred Heart (religious order) |
| MSC | IEEE Multi Conference on Systems and Control |
| MSC | Microsoft Compiler |
| MSC | Marine Science Center (of Northeastern University; Nahant, MA) |
| MSC | Mail Stop Code |
| MSC | Management Standards Centre (UK) |
| MSC | Major Subordinate Commands |
| MSC | Major Subordinate Command |
| MSC | Matière et Systèmes Complexes (French) |
| MSC | Mobile Services Switching Center |
| MSC | Marrow Stromal Cell (biology) |
| MSC | Maricopa Skill Center (Phoenix, Arizona community college system) |
| MSC | Message Service Center |
| MSC | MacNeal-Schwendler Corporation |
| MSC | Main Service Channel |
| MSC | Maryland Science Center |
| MSC | Microscan |
| MSC | Medicaid Service Coordination |
| MSC | MIDI Show Control |
| MSC | Marine Safety Committee |
| MSC | Marine Safety Center (US Coast Guard) |
| MSC | Mass Storage Controller |
| MSC | Mandatory Settlement Conference (Civil Tort Cases) |
| MSC | Meteorological Synthesizing Centre |
| MSC | Meritorious Service Cross (Canadian naval decoration) |
| MSC | Merchant Service Charge |
| MSC | Maritime Security Council |
| MSC | Mediterranean Shipping Company SA (container shipping line) |
| MSC | Military Staff Committee (United Nations) |
| MSC | Multiprotocol Session Controller |
| MSC | Medical Students for Choice |
| MSC | Montana State College (Bozeman, MT) |
| MSC | Manufacturing Sciences Corporation (Oak Ridge, TN) |
| MSC | Microcomputers Systems Components (Germany) |
| MSC | Microsoft Configuration (file extension) |
| MSC | Monthly Service Charge(s) |
| MSC | Mass Storage Compliant |
| MSC | Mulch and Soil Council |
| MSC | Microprocessor Standards Committee (IEEE) |
| MSC | Mission Support Center |
| MSC | Mechanical Speed Control |
| MSC | Mount St. Clare College |
| MSC | Management Saved Console (Microsoft file extension) |
| MSC | Mesa Soccer Club (Arizona) |
| MSC | Moved, Seconded, and Carried |
| MSC | Marine Studies Consortium |
| MSC | Many Small Children |
| MSC | Mission Support Contract (cilivan support) |
| MSC | Malaysia Super Corridor |
| MSC | Management Systems Corporation |
| MSC | Minority Supplier Council |
| MSC | Medium-Specific Concentration |
| MSC | Marine Science Consortium, Inc. |
| MSC | Mobile Servicing Center |
| MSC | Marine Safety Council |
| MSC | Mississippi Central Railroad |
| MSC | MiCTA Service Corporation |
| MSC | Mackenzie Sports Club |
| MSC | Maintenance Support Center |
| MSC | Major Support Command |
| MSC | Multiservice Concentrator (Motorola) |
| MSC | Michigan Sugar Company (Saginaw, Michigan, USA) |
| MSC | Management Sectional Center |
| MSC | Maintenance of Service Charge |
| MSC | Medical Support Center |
| MSC | Minnesota Soaring Club (aviation) |
| MSC | Muswellbrook Shire Council (Australia) |
| MSC | Movimiento de Seglares Claretianos (Lay Clareton Movement) |
| MSC | Mammography Screening Center |
| MSC | Memphis Service Center |
| MSC | Material Service Center |
| MSC | Multiple System Coupling (IBM) |
| MSC | Materials Simulation Center (Pennsylvania State University) |
| MSC | Media Services Center |
| MSC | Model Schools Conference |
| MSC | Montreal Subaru Club |
| MSC | Main System Controller |
| MSC | Mobile Satellite Channel |
| MSC | Material Support Center |
| MSC | Market Sales Coordinator |
| MSC | Multicast for Small Conferences |
| MSC | Management Service Control (Sprint) |
| MSC | Microsoft Saved Console |
| MSC | Mission Systems Contract |
| MSC | Maroondah Secondary College (Australia) |
| MSC | Moorestown Soccer Club |
| MSC | Military Shipping Container |
| MSC | Maritime Surveillance Capability |
| MSC | Maritime Sector Commander |
| MSC | Minimum Service Commitment (Sprint) |
| MSC | Malay Speaking Circle |
| MSC | Metropolitan Spinal Clinic (Ringwood, Victoria, Australia) |
| MSC | Mechanical Systems Center |
| MSC | Materiel Status Committee |
| MSC | Materiel Support Command |
| MSC | Multi-Mode Source Controlled |
| MSC | Modified Spherical Coordinates |
| MSC | Minnesota Sportfishing Congress |
| MSC | Milestone Schedule Chart |
| MSC | Material Safety Code |
| MSC | Miscellaneous System Controller |
| MSC | Multiple Successive Correction |
| MSC | Maersk and Mediterranean Shipping Company |
| MSC | Miramonte Swim Club (California) |
| MSC | Manual Steering Column (Star Trek) |
| MSC | Master Solver's Club (Bridge card game) |
| MSC | Multiservice Connect |
| MSC | Medium Speed Channel |
| MSC | Major Systems Command |
| MSC | Master Specification Catalogue (US Navy) |
| MSC | Mode Select Circuitry |
| MSC | Management Services Consultants LLC |
| MSC | meningioma of region sinus cavernous |
| MSC | Martin-Stewart Contracting Ltd. |
| MSC | Minimal Subset Cut |
| MSC | Minesweeping, Coastal |
| MSC | Merchant Ship Characteristic |
| MSC | Multi-Staged Combustion |
| MSC | Media Simulated Calling |
| MSC | Montgomery Support Center |
| MSC | Motor Side Converter |