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MMP3 |
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15-17) Matrix metalloproteinase 3 is considered to play essential roles in the degradation of both aggrecan and collagen fibrils in the cartilage, the latter of which may be digested through the degradation of perifibrillar extracellular matrix components such as type IX collagen (6,7) and the activation of proMMP-1, (8) proMMP-9, (19) and proMMP-13. |
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